In a world facing all kinds of contradictions, the internationalization of all affairs and the process of globalization seem to be the fate of our time. The story becomes increasingly universal as our planet has become the global village announced by Mac Luhan two decades ago. The economy has become interdependent and there are a few problems that cannot be solved in isolation by any country. In the texts of the Revista Mexicana de Política Exterior, the challenges that globalization and interdependence represent in the country's foreign policy are exposed.