This issue of Revista Mexicana de Política Exterior addresses Mexico's participation in the United Nations Security Council during the period 2021-2022. It highlights Mexico's presidency in the Council, describing flagship events, conducted deliberations, controversies, and adopted resolutions. Articles on Council agenda topics are also included: pandemics, food security, and climate change; non-proliferation of nuclear, chemical, and biological weapons; the fragile situation in Mali and the Sahel; the women, peace, and security agenda; U.N. missions in Colombia and Haiti; the humanitarian crisis in Syria; resolutions on the Middle East; the armed conflict between Ukraine and Russia; peacekeeping personnel and mental health; and the issue of veto and Security Council reform.