To properly understand the relevance and impact of health regulation, it is necessary to study the different efforts that have been carried out in distinct latitudes, just like the multilateral cooperation in the subject. This is how it emerges the idea of this issue of the Revista Mexicana de Política Exterior, which is the result of a fruitful collaboration between COFEPRIS and the Ministry of Foreign Affairs, through the Matías Romero Institute. Its aim is to publicize different aspects of the health regulation in Mexico and Latin America to, from a humanistic perspective, build relations, extend the national interest in public health, encourage regional cooperation and promote science and innovation between the countries of the region.